Alternatives & Traditional

Posts tagged ‘minerals’

The Stomach Acid is a Waste Product Myth

I have seen a number of people erroneously claiming stomach acid is not necessary to the body and is in fact a dangerous byproduct in the body.  The myth was traced back to a Dr. Young. An article promoting this myth is found on his FaceBook page: https://www.facebook.com/groups/50864627953/permalink/10152914603067954/ .

This article is addressing the various myths being promoted by Dr. Young and will explain the importance of stomach acid in the body.

Let’s start with the claim that the stomach does not digest food. Digestion starts in the mouth and continues in the stomach and throughout most of the intestine. Therefore, I am not really sure what he means by the stomach not digesting food. If that is the case then wouldn’t the same apply to the mouth and intestines since enzymes are working in all these areas to digest the food? So where does Dr. Young think digestion takes place if at all?

As for his claims about the stomach alkalizing food this just further backs my belief that Dr. Young DOES NOT understand human physiology. Alkalizing of the chyme occurs in the duodenum, not the stomach.

When we ingest food or liquids stomach acid is released for a variety of reasons.:

-Stomach acid is needed to kill ingested pathogens.

-Stomach acid is needed to acidify certain nutrients such as minerals and the vitamins B6, B12 and folate for absorption. These B vitamins are required for methylation, which is essential for about 4,000 processes in the body including the production of more stomach acid.

Methylation is also required to prevent cancer, reduce the risk of heart disease, build up neurotransmitters and hormones, support energy levels and the immune system, for cartilage synthesis, etc.

And a lack of stomach acid decreases the conversion of silica in to orthosilicic acid (OA). Declining stomach acid leads to decreases in OA, which in turn leads to many of the conditions associated with aging such as osteoarthritis, osteoporosis, emphysema, diverticulitis, wrinkles, etc.

-Stomach acid is required for the protein digestive enzyme pepsin to function. Without sufficient stomach acid the proteins fail to break down properly leaving protein solutes that can trigger off immune reactions.

I have a write up on the benefits of stomach acid here:

http://medcapsules.com/forum/showthread.php?tid=2945

The chyme, which is a mixture of food or ingested liquids, stomach acid and enzymes is made acidic by the stomach acid for the above reasons. The chyme is then released in to the duodenum where pancreatic bicarbonate is released to neutralize the acids in the chyme. The duodenum IS NOT the stomach. The stomach only releases bicarbonate after digestion in the stomach is finished to neutralize whatever acid is left in the stomach since the stomach does not maintain a protective barrier 24 hours a day.

What really get me is how Dr. Young claims hydrochloric acid is a waste product when it is essential for many things in the body.

And he is wrong on most of what he claims the hydrochloric acid causes. Stomach acid DOES NOT cause indigestion nor reflux. A lack of stomach acid can cause these, which is why things that increase stomach acidity such as bitters, betaine HCl or vinegar are used to treat these conditions. See:

http://medcapsules.com/forum/showthread.php?tid=2632

Excessive stomach acid (hyperchlorhydria) is actually so rare that it is almost unheard of. Especially since stomach acid levels naturally decline with age and most people are acid deficient after the age of 40.

It was once thought that excess stomach acid was a cause of stomach ulcers. That myth was disproven decades ago!!!!!

Stomach acid only causes stomach ulcers when the stomach’s protective lining is not there to protect the stomach, such as when nonsteroidal anti-inflammatory drugs (NSAIDs) are used such as aspirin, ibuprofen (Advil, Motrin, Nuprin, etc), celecoxib (Celebrex), naproxen (Naprosyn), etc. These drugs inhibit hormones known as prostaglandins. Most people familiar with these hormones know that some are associated with inflammation since they dilate blood vessels, which can lead to leakage. But these hormones are also required for the production of the stomach’s protective lining.

If Dr. Young understood ulcer formation he would also know that the most common cause of ulcers is the bacteria Helicobacter pylori, which secretes highly alkaline and toxic ammonia to neutralize the stomach acid that would otherwise kill the bacteria.

Helicobacter pylori is also a primary cause of stomach cancer. Stomach cancer risk has been found to have a direct correlation to low or absent stomach acid, which is contrary to Dr, Young’s claim.

His claims in number 5 are simply laughable!!!!!

Apparently Dr. Young is also unaware of the fact that stomach acid is released with the ingestion of any food or liquid. Even the though of food can stimulate stomach acid release. This DOES NOT occur only with animal protein sources as he implies.

Then there is his contradiction. He claims earlier that the bicarbonate and the acid are produced in equal parts. But then he claims that as the stomach acid is released the bicarbonate is released in to the stomach to neutralize the acid thus inducing alkalosis and using up the alkaline reserves. First of all none of this is true. Then he continues with claiming the hydrochloric acid is taken up by the blood lowering the plasma pH, which is also complete nonsense. If that really happened we would all be dead. So how does he explain the alkaline reserves being depleted while there is still an excess of acid supposedly entering the bloodstream if they were produced equally? Using some common sense should tell him that if these two compounds are formed in equal amounts then this would also mean that the depletion of sodium bicarbonate would also mean a complete depletion of the stomach acid. In other words, if the salt forms one unit of bicarbonate and one unit of hydrochloric acid and one unit of bicarbonate will neutralize one unit of hydrochloric acid that would mean that a depletion of the bicarbonate reserves would mean a complete neutralization of ALL the stomach acid. In fact, this does not even take in to account the compounds in our diet that will neutralize the stomach acid such as carbonates, alkaloids, etc. in the diet that all neutralize acid. Therefore, the stomach acid would be depleted long before the bicarbonate. So where is all this hydrochloric acid coming from that is supposedly entering the bloodstream according to his bogus claims?

If Dr. Young really understood human physiology then he would also know that acid buffering bicarbonate is released in to the blood by parietal cells during stomach acid secretion leading to ALKALINITY of the blood, not acidosis as he claims. He should research the “alkaline tide”. Alkalizing bicarbonate is also produce in the blood. So again, how is acidosis occurring when stomach acid never enters the blood and even if it did the acid would be neutralized by the bicarbonate and the body’s pH would still be maintained through respiration and kidney function?

In fact, it is not the acid that is the danger as he claims, it is the base that has to be dealt with. See:

https://mcb.berkeley.edu/labs/forte/morphol.html

Then Dr Young refers to the Pishinger’s space as an “organ” when it is not an organ. A space is not an organ. Furthermore, if you look up Pishinger’s space the only sites that come up are the ones repeating his claims.

Dr. Young also refers to the acids from cells as waste again when in fact they are required for our health and existence.

Then Dr. Young claims there is no mention of any organs that store acids from metabolism and diet. So what? There is no reason to store these acids since they are utilized by the immediately. For example, we produce carbonic acid continually, which serves numerous purposes such as to buffer highly alkaline and highly toxic ammonia, to maintain circulation, to allow oxygen release from hemoglobin, to form more stomach acid for proper digestion and absorption, and for the production of bicarbonate!!!! Come on, this is BASIC human physiology he is not grasping!!!!!!

Then Dr. Young falsely claims the kidneys store acids. The kidney IS NOT a storage organ and DOES NOT store acids.

Dr. Young then goes on to falsely claim these acids are buffered then eliminated via the skin, urinary tract and bowels. See the contradiction in his claims? If the bicarbonate buffers were used up by stomach acid leading to an increase of hydrochloric acid in the blood leading to acidosis as he claims then where is the bicarbonate buffers coming from that are supposedly buffering those acids? There are no other buffers in the blood. And if there were they would be used up by the hydrochloric acid in the blood if t really made it in to the blood which according to Dr. Young is causing acidosis. How can you buffer the metabolism acids if acidosis is present? The answer is you cannot. Yet this is what Dr. Young is claiming. So not only does he need to learn some human physiology, he also needs to learn some basic chemistry.

Dr. Young contradicts himself yet again with claim number 7. If a high animal protein meal caused acidosis as he falsely claims then the excess hydrogen ions from the acidosis he claims would be excreted through the kidneys causing ACIDIC, not alkaline urine. Then Dr. Young goes on to claim a base being excreted in the urine, which is the alkalinity. So where is this Base coming from? Again that base would have to be bicarbonate, which he claims earlier is depleted by the hydrochloric acid. So again, where is this base coming from if his claim were true?

Dr. Young’s myth about tissue acidosis leading to disease has already been addressed a number of times. The vast majority of diseases arise in an alkaline, not acidic environment.

On claim 8 Dr. Young talks about lactic acid during heavy exercise that in order to be absorbed by the collagen fibers as he falsely claims would have to be excreted. The lactic acid being excreted by muscles during heavy exercise myth was disproven decades ago!!!! During heavy exercise non-acidic lactate is formed, which IS NOT the same thing as lactic acid even though the terms get used interchangeably frequently. The burning sensation people feel IS NOT from lactic acid but rather an excess of hydrogen ions (protons).

Same with Dr. Young’s false claim that the lactic acid is stored in the tissues. How can this be occurring when no lactic acid is secreted from cells?

Dr. Young’s claim in 9 starts out bogus then gets outright bizarre where he refers to alkaliphile glands. Alkaliphiles are microorganisms, NOT glands!!!! So it looks like he is making up his own terms along with his “facts”.

In claim 9 Dr. young further incorrectly states that the body’s alkaline reserve status can be determined by blood or urinary pH testing. This is totally ludicrous!!!!! Salivary pH is affected by the amount of bacteria in the mouth so things such as brushing your teeth will make the saliva more alkaline. So will drinking water, thinking of certain foods, etc. Dry mouth increases acidity as alkaline saliva normally washes away acid forming bacteria in the mouth. Urinary pH is affected by hydration levels, certain supplements and medications and by bacteria in the urine. Urinary tract infections lead to highly alkaline urine as the bacteria use the enzyme urease to split urea in to highly alkaline ammonia. The alkalinity helps the bacteria, as with most pathogens, to survive.

Claim 10 starts out right away with a major error since this IS NOT how the blood pH is maintained. Again, pH is maintained through respiration and kidney retention or elimination of hydrogen ions (protons). If the acids were being pushed in to the connective tissues or spaces

And how can the blood give the urine the same amount of acidity if the tissues, such as the kidneys store the acids as Dr. Young claims?

Urinary pH DOES NOT reflect tissue pH. Tissue pH is maintained by the blood, which again does not reflect in urinary pH.

In claim 11 he refers again to “alkaliphile organs”. Again alkaliphiles ARE NOT glands, they are microbes.

Next Dr. Young refers to hyperproteinization leading to people looking like prunes as they age. More garbage!!! Wrinkles are the result of a lack of orthosilicic acid and/or ascorbic acid, which in turn leads to a loss of collagen and elastin in the skin. Orthosilicic acid loss occurs from a DECLINE in stomach acid since stomach acid aids in the conversion of silica in to the usable orthosilicic acid.

Apparently Dr. Young does not understand ORP either. Without going in to long explanation ORP is simply a sales tool often misrepresented to sell products. It DOES NOT measure all the antioxidants of the body.

In claim 12 Dr. Young talks about the acids being stored again, which is not true, the alkaline reserves being depleted that again is not true and again contradicts Dr. Young’s other claim of acids being excreted in to the urine at the same amount that is going in to the blood. Again, how can X amount of acid enter the blood and X amount be excreted in the urine if Y amount of acid from X is being stored in the tissues?

Most of the claims up to number 18 are just regurgitated proven wrong already claims.

I find it interesting in claim 18 though that Dr. Young mentions pH regulation by respiration and by the kidneys. If he is aware of these pH regulators then he should also be aware of the fact that this goes against his claim about HCl entering the blood leading to acidosis. Even if it were true that the acid could enter the blood the body responds to even the slightest shift in pH by adjusting respiration to either increase or decrease the pH of the blood. Since there are no reserves involved there are no reserves to be depleted as he claims. Same for kidney function, which is the second primary means of pH regulation.

Claim 20 does not make any sense either. Sodium bicarbonate IS NOT reabsorbed. It is neutralized by acid. The blood maintains bicarbonate levels, not sodium bicarbonate in the blood. Note that he even points this out in claim 21 where it states “CO2 + H2O = H2CO3 = HCO3 + H+”. Where is the sodium (Na)? It’s not there because he is talking about the blood bicarbonate, not sodium bicarbonate that he is incorrectly claiming is absorbed back in to the bloodstream.

In claim 22 Dr. Young claims ammonia is trapped and concentrated in the kidney. Again, the kidney DOES NOT store things, especially highly alkaline and highly toxic ammonia that would kill the tissues if it built up like Dr. Young is claiming.

In claim 23 Dr. Young claims and 90% of the carbon dioxide is used by the body to “reabsorb alkaline minerals and make sodium bicarbonate for buffering gastrointestinal and metabolic acids.” What is needed to absorb these alkaline minerals? STOMACH ACID!!!!! So once again Dr. Young is contradicting himself.

In claim 24 Dr, Young states: “Of all the ways the body can buffer metabolic and dietary acids, the excretion of protein (the eating of meat and cheese) generated acid residues is the only process that does not add sodium bicarbonate back into blood circulation. “.

First of all as pointed out sodium bicarbonate is neutralized by the acids, not reabsorbed in to the bloodstream. Blood bicarbonate (note not sodium bicarbonate) is formed in the blood from carbonic acid.

Secondly, what else is needed for sodium bicarbonate production? Sodium chloride salt, which is abundant in meats and dairy. So again his claims are contradictory.

At least in claim 25 Dr. Young gets something right when he states “Human Body is an acid producing organism by function”. The body is composed of acids, runs on acids, requires acids to maintain circulation and oxygen delivery, for maintaining health and tissues, for detoxification, etc.

What Dr. Young does not seem to understand is the fact that we cannot live or even exist without acids. Or the fact that ALL foods are metabolized in to acids, not just animal proteins.

-James Sloane

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Top 5 Worst Internet Health Information Sites: Curezone.org Part 2: Alkaline/Acid Support Forum Part 1

The whole concept of acid-alkaline balance is another highly misunderstood are of health.  Unfortunately, sales sites in particular have presented so much information to promote their products that the real truth has become so muddy.  For example, the multilevel marketing company Kangen International and sellers of their products have posted various videos and articles full of false and misleading information.  I have addressed their claims various times in the past including this review of some Kangen water promotional videos:

http://medcapsules.com/forum/showthread.php?tid=2762&pid=3782#pid3782

I have also covered other Kangen myths and posted other links with evidence in this post:

http://curezone.com/forums/fm.asp?i=1661838#i

And have additional information in this post:

http://curezone.com/forums/fm.asp?i=1531679

I addressed the myths on another site trying to claim acids were the cause of so many diseases here:

http://medcapsules.com/forum/showthread.php?tid=2761&pid=3781#pid3781

The principle of Kangen alkaline water is that the mineral hydroxides formed will alkalize the body preventing disease.   Hydroxides though are not only dangerous directly, but can also lead to secondary health issues.

Hydroxides cause tissue damage directly because they are some of the strongest free radicals known and are caustic, chemically burning the tissues.  For example, Milk of Magnesia is used as a laxative because it is it consists of magnesium hydroxide.  Magnesium hydroxide neutralizes the stomach acid leading to a separate set of health problems.  What does not get neutralized itself by reaction with stomach acid reaches the intestines where it chemically burns the intestinal wall.  This leads to an influx of water in to the intestines and increased peristalsis.  The burning of the intestinal wall leads to an increased risk of problems such as leaky gut and cancer and diarrhea can lead to electrolyte imbalances if used too frequently.

Kangen International has provided a great example of how easy it is to mislead people.  Kangen claims they received approval from the Japanese Ministry of Health (JMH) to use these machines and claims that they are in nearly every home in Japan.

The fact though is that the JMH has NEVER issued approval to any alkaline water devices.  Yet, Kangen posted a tiny picture of what they claimed was the approval certificate on their site.  If it was not a certificate of approval from the JMH then what was it.  They made sure the picture of the document was too small to read so I copied the picture in to a Word document then enlarged the photo.  The document was merely a business license to make the machines, nothing doing with approval from the JMH as claimed.

I have a friend that comes to visit from Tokyo several times a year so I asked about these machines.  My friend had no idea what I was talking about and said most people simply drink tap water there.  Therefore, I did some more research and found that only around 10% of the homes in Japan have alkaline water machines.  That is a big difference from the Kangen claims of being in nearly every household in Japan.

Those are just a few of the many lies Kangen has been found to have made regarding their machines as well as pH and health.

In reality the body RARELY ever goes acidic, or too alkaline for that matter.  This is because either excess acidity, below 6.8, or excess alkalinity, above 7.8 will kill a person.  Therefore, the body has numerous redundant systems to maintain its narrow pH range.  Although, excess alkalinity is considered more dangerous than excess acidity since the body has various means to reduce acidity, but virtually nothing to combat excess alkalinity.

Respiration is the body’s primary means of pH regulation.  If the blood starts to get acidic our respiration increases to blow off carbon dioxide(CO2), which reduces carbonic acid and acidic hydrogen ions.  If the body starts to become too alkaline the respiration slows down to retain CO2, increasing carbonic acid, and decreasing hydrogen ion removal.  Other means the body can use to maintain pH include:

  • Buffering acids with bicarbonate.
  •  Excreting hydrogen ions, carbonic acid or bicarbonate out through the urine or retain them to adjust pH.
  • The pH is also regulated by proteins that either bond or release hydrogen ions in response to pH imbalances.
  • Using phosphates and hemoglobin as buffers
  •  As a last resort excess acidity can be buffered by the minerals present in bone.

References:

http://dwb4.unl.edu/Chem/CHEM869R/CHEM869RLinks/www.usyd.edu.au/su/anaes/lectures/acidbase_mjb/control.html
http://www.chemistry.wustl.edu/~edudev/LabTutorials/Buffer/Buffer.html

This is why we rarely see acidosis (overly acidic blood) or alkalosis (overly alkaline blood).

Acute acidosis can occur with severe vomiting and diarrhea, ketoacidosis, inadequate oxygen intake or utilization (respiratory acidosis), rhabdomyolosis, kidney failure and by poisoning with certain chemicals.

Acute alkalosis can occur with over consumption of hydroxides including alkaline waters, consumption of milk with hydroxides, overuse of carbonates such as antacids or baking soda, prolonged vomiting, excessive aldosterone secretion, diuretic use and hyperventilation.

One Curezone poster claimed that all disease was the result of the lymphatic system becoming too acidic.  The pH of the lymphatic system though is kept slightly more alkaline than the blood.   Therefore, lymphatic acidosis does not occur.

Interestingly, this same poster claims that “nitrate toxicity” poisons people by the formation of methemoglobin that locks up oxygen leading to death by oxygen insufficiency.  Actually, it is nitrite that does this, not nitrate.  And what promotes nitrite formation?  A high (alkaline) pH in the stomach.  Yet this poster was pushing an alkalizing drink made with caustic calcium hydroxide.  Even though his recipe also included lemon juice to buffer some of the hydroxide, without a pH meter it would be impossible to tell if the solution was alkaline, neutral or acidic.  If maintained as an alkaline drink as intended the calcium hydroxide would not only chemically burn the tissues, but it would also neutralize the stomach acid leading to increased nitrite and thus methemoglobin formation.  Therefore, the drink he was advocating promoted the formation of the nitrites he was claiming was poisoning and killing people.  I addressed his claims here:

http://curezone.org/forums/fm.asp?i=1486784#i

And his other claims here:

https://medreview.wordpress.com/2013/02/27/top-5-worst-internet-health-information-sites-curezone-org-part-2-ask-moreless/

To make matters worse, neutralizing stomach acid interferes with the absorption of certain nutrients needed to produce more stomach acid.   This leads to a more chronic decline of stomach acid further promoting nitrite and methemoglobin production.  These same acid dependent nutrients are also required for over 4,000 other reactions in the body that include immunity, energy formation, controlling water balance, prevention of heart disease, etc.  This is why I would never recommend this protocol and don’t recommend things that neutralize the stomach acid including Kangen water, baking soda, magnesium oxide or calcium carbonate (oyster shell, coral, dolomite) supplements, antacids or acid blockers.

Because chronic acidosis is so rare and diseases are so prevalent, even common sense should tell us that acidosis is not a cause of most diseases.  Most often it is a byproduct of a disease, not a cause.

Still myths surrounding alkalinity being healthy abound.  For example, the persistent myth that cancer is caused from acidity and killed by alkalinity.  If this is the case though then why do cancer cells have a more alkaline internal pH than healthy cells?  Why aren’t people more prone to chronic acidosis such as those with COPD all dying of cancer?  Why do strict vegetarians and raw foodists who consume “highly alkaline diets” still getting cancer?  The answer is simple.  Our pH, which rarely goes acidic or alkaline has nothing to do with cancer formation or treatment.

In fact, the ulcer and cancer causing bacteria Helicobacter pylori (H. pylori) protects itself from stomach acid by secreting highly alkaline ammonia to neutralize the stomach acid.  As pointed out previously H. pylori is known for causing cancer.  Therefore,  we have an example of cancer forming in an alkaline environment.  On the other hand stomach cancer is very rare in younger people who have higher stomach acid levels.  This is the result of most pathogens, including cancer causing pathogens being destroyed by sufficient stomach acid.  Stomach acid levels decline with age and this process is accelerated by the use of acid neutralizing substances such as ionized alkaline water and antacids as well as acid blockers (proton pump inhibitors more apt to be taken by older people.

This is also evidenced by the fact that wild dogs in particular can eat bacteria ridden meats that they may be scavenging long after the death of the animal or that they stored for later eating.  The reason these dogs can consume these meats full of bacteria that would poison a human is because dogs produce significantly higher levels of stomach acid than humans.  These higher levels of acid effectively kill the bacteria they are ingesting preventing them from becoming sick from food poisoning.

Another common myth heavily promoted on alkaline sales sites is that most pathogens are killed by acids and thrive in an alkaline environment.  The reality though is that the opposite is true.  This is why the parts of the body that help protect us from pathogens are normally acidic.  These include the female organs, skin, stomach, parts of the intestines, and sinuses.  Urine is normally acidic to control pathogens and to prevent kidney stones.  One of the symptoms of bacterial urinary tract infections is an alkaline urinary pH since the bacteria split urea in to highly alkaline ammonia and other alkaline substances to protect themselves from acidity.

Skin infections can occur when the skin loses it natural pH mantle that keeps it healthy and controls pathogens.  Soap for example removes the acid mantle.  People who repeatedly wash their hands with soap or have their hands in water a lot can develop skin infections as the removal of the acid mantle leads to cracks in the skin and increased pathogen growth.

Other means by which alkalinity can promote disease include:

When people have their gallbladders removed they become at a much higher risk of intestinal cancers.  Why?  Because caustic, alkaline bile gets dumped in to the intestines instead of being squirted in as needed.  This dumping of the alkaline bile burns the intestinal wall repeatedly leading to the increased risk of cancer.

Despite being alkaline, high serum calcium can lead to various health issues.  These include high blood pressure, mental fogginess, constipation, etc.

Excessive alkalinity in the blood or urine can also allow minerals to precipitate out where they do not belong leading to various health problems.

Alkalizing methods, such as carbonates and hydroxides including those from alkaline waters, neutralize the stomach acid.   Ironically,  sufficient stomach acid is needed to absorb many of the same minerals the alkalosis advocates claim people need to be healthy.  Furthermore, a lack of stomach acid inhibits the absorption of the B vitamins B6, B12 and folate.   Not only does this lead to nervous system disorders, but also other problems including cervical dysplasia in women, heart disease from elevated homocysteine, neurological disorders,  cancer and immune suppression from decreased methylation………

Lack of stomach acid also blocks the proper breakdown of proteins since the protein digestive enzyme pepsin cannot work without sufficient stomach acid.   This can lead not only to protein deficiencies, but also partially digested proteins entering in to the blood stream triggering allergic reactions.   These allergic reactions further stress the adrenals leading to immune suppression, increased inflammation, chronically low blood pressure or orthostatic hypotension, thyroid issues, blood sugar problems, water retention and other health problems.

I have seen some people claim that neutralizing the stomach acid with things such as alkaline waters will simply cause the body to generate more stomach acid.   This is not completely true.   Keep in mind that B6, B12 and folate require sufficient stomach acid in order to absorb.   These B vitamins though are also required to produce stomach acid.   When people wipe out their stomach acid they interfere with the absorption of these B vitamins, which in turn interferes with stomach acid formation.   This in turn interferes with the absorption of these B vitamins………….   It is vicious downward spiral.   The elderly are the most at risk since stomach acid levels gradually decline with age.   People on acid blockers and antacids or that are neutralizing their stomach acid through other means are also at higher risk for the same reason.

If the alkaline supporters think about it why did people start pickling foods?  It was not for flavor.  Foods were pickled because the acids produced by the fermentation killed any pathogens or microbes that would spoil the food.

Boric acid has been used to treat infections by Candida species:

http://care.diabetesjournals.org/content/30/2/312.long

Acids have also been shown to control Aspergillus fungi as well:

http://www.ncbi.nlm.nih.gov/pubmed/20943191

http://mic.sgmjournals.org/cgi/content/abstract/155/9/3100

“Utilizing various free sialic acids and other carbohydrates, sialic acid derivatives, sialoglycoconjugates, glycoproteins, -keto acid related compounds and amino acids we have found that the binding of A. fumigatusconidia to type IV collagen and fibrinogen was inhibited by (i) glycoproteins (in a sialic acid-independent manner), and (ii) free sialic acids, glucuronic acid and -keto acid related compounds. However, inhibition by the latter was found to be the result of a shift in pH from neutral (pH 7.4) to acidic (less than pH 4.6) induced by the relatively high concentrations of free sialic acids, glucuronic acid and -keto acid related compounds used in the binding assays. This suggests that previous reports describing inhibition of A. fumigatus conidia binding by free sialic acid may actually be due to a pH shift similar to that shown here. ”

http://content.karger.com/ProdukteDB/produkte.asp?Doi=232521

Three different stages were found during growth of Aspergillus fumigatus as characterized by the changes in pH of the medium: (1) An acidic phase (phase I); (2) a second phase (phase II) during which the pH rises till values around pH = 8.5; (3) a third phase (phase III) during which the pH remains constant or drops slightly. During phase I a fast appearance of certain antigenic components was found that is ascribed to an active process of excretion. Additional antigenic components appeared in the culture medium after lysis of the microorganisms (phases II and III). Lysis of the microorganisms and appearance of antigenic components are dependent on the glucose concentration of the medium.

http://130.88.242.202/medicine/Aspergillus/articlesoverflow/20038606.pdf

Title: Aspergillus fumigatus survival in alkaline and extreme zinc-limiting environments relies on the induction of a zinc-homeostasis system encoded by the zrfC-aspf2 genes.

“Interestingly, this would explain the slightly reduced growth ability of the AF891 strain expressing aspf2 in acidic media (Fig. 9B).”

A great example exposing both the alkalinity prevents cancer and alkalinity kills pathogens myth is the cancer causing Helicobacter pylori bacteria.  Not only does this bacteria cause cancer, but it cannot survive in an acidic environment.  Therefore, once H. pylori screws in to the stomach wall the bacteria secretes highly alkaline ammonia to neutralize stomach acid to protect itself.  Despite the alkalinity created by the ammonia the bacteria can still cause cancer.

People also need to understand that when they try to force the pH in to an alkaline state they just put more stress on the body.   This is because the body now has to work harder to deal with the excess alkalinity since alkalosis is a dangerous condition.

To make things worse, most of the products out there designed to alkalize the body also neutralize beneficial acids such as stomach acid and the flora acids that control Candida.

Neutralizing the stomach acid leads to:

  • Nutritional deficiencies.  Primarily proteins, minerals and vitamins B6, B12 and folate that all require sufficient stomach acid for proper absorption.
  • increased pathogens entering through the digestive system
  • Improper protein digestion since the protein digestive enzyme pepsin cannot work without sufficient stomach acid.
  • Increased risk of allergies from incompletely digested proteins that can enter the bloodstream through the intestines and act as antigens to the immune system.
  • Acid reflux from longer digestion time and increased fermentation in the stomach.
  • Increased risk of cancer, heart disease and inflammation from decreased methylation, etc.
  • Suppressed immune function from decreased nutrition and methylation.
  • Further declines in the production of stomach acid due to decreased methylation required to form stomach acid.

In addition, over alkalizing the system can promote candidiasis.  There is a very persistent myth that Candida albicans cannot survive a high (alkaline) pH.  The fact is that C. albicans can survive very acid to extremely alkaline pH.  The primary difference is the form the Candida takes on dependent on the pH.  Candida is a dimorphic microbe meaning it can exist in two forms.  Candida can exist as either yeast or fungus depending on the pH of the terrain it is in.  At a low (acidic) pH C. albicans remains in a benign yeast form and its growth is inhibited as the Candida growth gene is turned off.  When C. albicans is exposed to a high (alkaline) pH the Candida gene is turned on and the Candida morphs in to its pathogenic fungal form.  In its fungal form the Candida develops finger-like projections known as hyphae that allow the Candida to dig in to and damage tissues.  C. albicans hyphal growth is inhibited at an acidic pH of 4 or below reducing tissue invasion and damage.  I have compiled some research from non-commercial sites to prove these facts.  The growth of C. albicans in an alkaline environment, as well as an acidic environment in a pH range of 2 to 10:

http://ec.asm.org/cgi/content/full/5/9/1550
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=232444

http://www.ncbi.nlm.nih.gov/pubmed/15189995?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_RA&linkpos=1&log$=relatedarticles&logdbfrom=pubmed

http://www.ncbi.nlm.nih.gov/pubmed/10629054?ordinalpos=11&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

http://www.springerlink.com/content/06crgmq4x3nj2820/

“In vitro, C. albicans can thrive over a remarkably wide range of extracellular pH, at pH values of 2-10 (Odds 1988)”. They also point out that alkalinity promotes hyphal growth of C. albicans.

http://www.springerlink.com/content/j5v6h012235h3576/

“Upon response to environmental stimuli C. albicans can switch between yeast-like and filamentous, hyphal growth. This allows C. albicans to generate niche specific responses, form biofilms, adhere, and invade epithelial tissues. ”

It is this switch to the hyphal growth, from alkalinity, that allows C. albicans to become pathogenic by more readily invading tissues:

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=97632
http://www.cell.com/current-biology/abstract/S0960-9822(06)00252-1

Hyphal growth has been shown to be inhibited at the acidic pH of 4 in all strains of C. albicans showing that an acidic pH helps to prevent C. albicans from being pathogenic.  An alkaline pH on the other hand promotes pathogenesis of C. albicans as it promotes hyphal growth. The article from the following link points out what I have been trying to explain to people for decades.  Stomach acid helps to control pathogen growth, including Candida.  The same applies to the skin, which is normally slightly on the acidic side.  When the pH is raised to the alkaline side candidiasis of the skin is promoted.

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1770313

“In tissue samples from mucosal surfaces with a non-acidic pH, such as the tongue, oesophagus, intestine, and most skin areas, filamentous forms of C albicans predominated, and most of them exhibited both 1H4 immunostaining and an invasive phenotype (fig 3A ). In internal organs having a non-acidic pH (liver, lung, heart, and thyroid) from patients with systemic candidiasis, variable numbers of yeast cells were found, together with hyphae or pseudohyphae in virtually all cases. In these tissues, both yeast and filamentous forms showed strong 1H4 immunoreactivity (fig 3B , C). In contrast, in those tissues with an acidic pH, such as the stomach and collecting ducts of the kidney, the predominant form of C albicans was the blastospore (yeast). Interestingly, in these locations yeast cells essentially showed no 1H4 immunoreactivity (fig 3D , E). However, when adjacent tissue invasion was present, hyphae or pseudohyphae were the predominant form.”

“The ability to undergo transition from the yeast to the hyphal form appears to be crucial in the pathogenesis of invasive candidiasis. 4– 6 Both yeast cells and hyphae are found in infected tissues and contribute to pathogenesis. Yeast cells are better suited for rapid haematogenous dissemination, but together with hyphal elements they are also capable of breaching epithelial and endothelial barriers to cause extensive organ damage. 4 During the infectious process, yeast cells and hyphae may encounter different microenvironments within the host. At acidic pH, C albicans grows mostly in the yeast form; at an alkaline pH, it grows primarily in the filamentous form. 2, 6, 7 Gastric acid provides an effective barrier to most microorganisms (normal gastric pH values are 1–3.5). In contrast, achlorhydria and the use of H2 antagonists, which raise gastric pH, have been found to be associated with a higher proportion of invasive gastric candidiasis. 17 Similarly, although the skin is relatively inhospitable to fungal growth, 18 the experimental increase of skin surface pH yields more pronounced cutaneous candidiasis in human volunteers. 19”

Another risk of fungal Candida overgrowth is the increased risk of leaky gut syndrome.  As the hyphae of fungal Candida dig in to the intestinal walls the damage leads to increased intestinal inflammation.  In turn the intestines become more permeable and allow antigenic protein solutes to absorb through the intestinal wall in to the bloodstream.  These antigenic proteins can then trigger off adverse immune reactions such as allergic responses.

Top 5 Worst Internet Health Information Sites: Curezone.org Part 2: Ask Moreless

In my opinion the most dangerous sites on Curezone are the Ask Moreless forum, the Liver Flush Support forum, the Cancer Support forum, the Alkaline/Acid Support forum and in my opinion the most dangerous forum the Iodine Supplementation Support Forum by VWT Team.

The basis of the Moreless forum was that all disease was caused by acidity and that a drink composed of calcium hydroxide (lime), lemon juice, organic unsulfured molasses and kelp was a cure-all.

Moreless was also well known for making up his own science and promoting it as fact.  Some of my favorite claims by Moreless were:

Moreless:  The more hydrogen present in a substance the more acidic it is.

Fact:   As I pointed out to Moreless hydrochloric acid contains one hydrogen atom and it is quite acidic.  On the other hand ammonium hydroxide contains 5 hydrogen atoms and yet is highly alkaline.

Moreless:   Sunlight is acidic.

Fact:   Sunlight does not have a pH.  The sun does contain a lot of hydrogen, which was the basis Moreless used for this claim.  But sunlight consists of photons, not hydrogen and therefore does not have a pH.

Moreless:   Acidity turns the tissues in to a puddle of goo.

Fact:  Many parts of the body are naturally acidic and do not turn in to goo.  I asked Moreless about this and why we don’t turn to goo from the acidic protons when we run but he never replied.

Moreless:  High brix foods are healthier than low brix foods.

Fact:  Brix is simply a measurement of sugar content.  As was pointed out to Moreless  Coca Cola has a higher brix reading than produce we consume, but this does not make it healthier.

Moreless:  Nitrogen is a protein.

Fact:  Nitrogen is a gas, not a protein.  Proteins do contain nitrogen though.

Moreless:  Iodine is an acid.

Fact:  Elemental iodine does not have a pH.

Moreless:  Alcohol is a hydrocarbon.

Fact:  Hydrocarbons consist solely of hydrogen and carbon.  Because alcohol also contains oxygen it is not a hydrocarbon.

Moreless:  “Now remember that our body does NOT absorb the foods we eat or the minerals we take, but ONLY the Energy, which becomes Released from our foods or Minerals we ingest!”.

Fact:  If we did not absorb the compounds such as sugars, amino acids and minerals from our foods then there would be nothing to form our tissues, bones, hormones, neurotransmitters, etc.   In other words we would not even exist.

Moreless:  Fats are carbohydrates.

Fact:  Fats are composed of fatty acids.  Carbohydrates are long chain sugar molecules.   They are not the same thing.

Moreless:   “Absolutely No Rock or Mineral in rock form or in food form can enter into our body tissues until this mineral has become Released from the food or Rock as Energy!”

My response:   “Wrong again. I can drink a mineral salt and it will absorb with no problem.  Do the minerals have to react with the stomach acid to be utilized by the body?  That depends on the form it is in.  If the mineral is chelated then it will absorb in that chelated form. If it is in a soluble salt then it will absorb as that salt.  If it is in the form of a hydroxide whatever can react with an acid to form a salt can be absorbed, and the rest will pass unabsorbed.  This is why calcium and magnesium hydroxides are so poorly absorbed, especially as we age.  Then we can also demonstrate that this claim is bogus by the fact that minerals given intravenously are still utilized by the body even though they are being put in to an alkaline environment and they are not being reacted with an acid. “

Moreless frequently talked about the dangers of nitrates and nitrites claiming that they led to methemoglobin production causing animals to suffocate.  I found the link where he got the information but he left out the part where is clearly stated that alkalinity in the stomach promoted nitrite formation.  Therefore, by his own argument his alkalinizing drink would poison people:

http://curezone.com/forums/fm.asp?i=1449606#i

http://curezone.com/forums/fm.asp?i=1449657#i

Here are links to some of the other weird and wild claims made by Moreless:

http://curezone.com/forums/fm.asp?i=1467298#i

http://curezone.com/forums/fm.asp?i=1467777#i

http://curezone.com/forums/fm.asp?i=1467369#i

http://curezone.com/forums/fm.asp?i=1467791#i

http://curezone.com/forums/fm.asp?i=1482445#i

http://curezone.com/forums/fm.asp?i=1415913#i

http://curezone.com/forums/fm.asp?i=1486171#i

Most of what Moreless posted was in a way hilarious because it was just so ridiculous.  On the other hand it was scary to think he was giving health advice and people were actually following him like he was their God.  Here are some examples I addressed:

http://curezone.com/forums/fm.asp?i=1468313#i

Moreless is very anti-science and thinks that his supposed success testimonials are the only proof needed to show he knows what he is talking about.  One problem with this though is that Moreless was famous for deleting posts where people reported adverse effects from his protocol, and then banning anyone reporting adverse effects.  Here is one example though of someone being hurt by the Moreless protocol that was posted on my forum so it could not be erased or edited:

http://curezone.com/forums/fm.asp?i=1495260#i

Moreless was also famous for re-wording other people’s messages on his forum so that it would appear the person was agreeing with Moreless or praising his protocol.  It was these actions that finally got Moreless banned from Curezone.

Furthermore, testimonials even if true are not proof of anything as I explained in this post:

http://curezone.com/forums/fm.asp?i=1470145#i

Moreless relied heavily on recruiting to try his protocol by touting all the testimonials that he had.  A big problem with this though is that there was no way to verify if the testimonials were real or if he had written them himself or edited people’s posts to make them sound positive, which he was known for doing.

I did run across this post from a supporter who had a change of heart:

http://curezone.com/forums/fm.asp?i=1709883#i

The biggest concern with the Moreless protocol was his recommendation to use calcium oxide (lime) to make a drink he wanted people to ingest to alkalize the body.   Calcium oxide is the same stuff used to make cement and when you read the bags it clearly warns about not getting it in contact with tissues.  The reason is that calcium oxide when it comes in to contact with water forms calcium hydroxide.  Hydroxides are very caustic and chemically burn the tissues.  Damage from consuming calcium hydroxide can appear immediately or in some cases may not show up for weeks or months.

The danger is not only from the caustic action of calcium hydroxide.  Calcium hydroxide also reacts with stomach acid neutralizing the stomach acid.  Stomach acid is important for a number of reasons, which I addressed in this post I wrote on the subject:

http://medcapsules.com/forum/showthread.php?tid=2945

Neutralizing the stomach acid on a regular basis can lead to numerous health problems including nutritional deficiencies, allergic responses, heart disease, increased risk of infections, etc.  These side effects can result from the inability to absorb certain nutrients needed for tissues such as bone.   The vitamins B6, B12 and folate are all involved in the process of methylation, which is required for around 4,000 methylation reactions in the body.  These include controlling allergic responses, digestion, energy formation, immune regulation, reduction of heart disease promoting homocysteine, hormone and neurotransmitter formation, etc.  All three of these vitamins though require sufficient stomach acid for their absorption.  Most pathogens are controlled by acidity and thrive in alkalinity.  Ingesting calcium hydroxide poses a dual danger here.  First of all the hydroxide can burn the tissues damaging them and making them more prone to infection.  In addition, the calcium hydroxide can neutralize the acids that normally help to control pathogens further increasing the risk of infections.

Moreless does recommend adding some lemon juice to his drink, which does contain citric and malic acids.  These mild organic acids will balance out some or all of the calcium hydroxide depending on the amount added.  The problem though is that unless the person has a pH meter to monitor the pH as the lemon juice is added it is impossible to know when enough of the lemon juice is added to neutralize all the caustic calcium hydroxide.  Don’t add enough of the lemon juice and the drink is still caustic.  Add too much and the drink will be acidic, which according to Moreless the acids will turn the body in to a puddle of goo.  Of course I am being sarcastic in the later since the acids produced by the body or that are found in lemon juice will not dissolve the body despite what Moreless claims.  Still there is the risk of hydroxide damage if insufficient lemon juice is added.

I never understood why Moreless did not have people just start with calcium citrate in the first place, which is readily available, is the main salt created by the reaction of calcium hydroxide and lemon juice and does not present the danger of caustic burns.

Various people had complained of being harmed by using the Moreless protocol, but many of the posts were deleted by Moreless.   Some reports can still be found on other boards though that Moreless did not control and I have a message sent to me by a woman asking for advice after being hospitalized for injuries sustained after following the Moreless protocol.

Two other things that really concern me about the Moreless protocol are the high amount of calcium and the iron from the blackstrap molasses.

Calcium is important to the body, but like anything can be a problem if in excess or not balanced.  Calcium is a muscle contractor for the body.  For example, the process of rigor mortis when a person dies involves the influx of calcium in to the muscles causing them to go in to a strongly contracted state until enzymes finally break down the muscle tissue.   Excessively high serum calcium can cause confusion, depression, high blood pressure, increased risk of asthma attacks, constipation, migraines, muscle cramps, etc.  Calcium channel blockers (CCBs) are used to treat various conditions such as high blood pressure and migraines because they prevent calcium from entering the muscle tissue of blood vessels keeping them relaxed.  In holistic medicine and even in hospitals for the treatment of preeclampsia associated hypertension (high blood pressure) magnesium is used to lower calcium induced high blood pressure.

My concern here is that the high amount of calcium poses to many potential problems primarily from calcium induced constriction of blood vessels.  The resultant decrease in blood flow could theoretically even increase the risk of heart attacks and strokes as other blood vessel constricting agents are known for.  Because of this calcium should always be balanced out with sufficient magnesium to maintain the muscle regulatory actions of calcium-magnesium.

As with calcium, iron is essential to the body but dangerous in excess.  Excess iron can lead to increased infections, oxidative tissue damage and can promote cancer.

There is also a condition that used to be considered very rare but is now considered common known as hemochromatosis.  In this condition there is a buildup of excess iron in the body leading to various health problems and can be fatal.  People with hemochromatosis are advised to avoid iron sources and often undergo regular phlebotomy to remove excess iron from the system.

The Benefits of Stomach Acid

Stomach acid is present to:

1. Help protect the body from pathogens that would otherwise enter through the digestive system.  Many pathogenic bacteria, such as E.  coli and H. pylori THRIVE in an alkaline environment.  This is why E. coli lives in the alkaline environment of the intestines and H.  pylori secretes ammonia to neutralize stomach acid to protect itself.  Reducing stomach acid just makes it that much easier for these pathogens to set up shop in the body where they DO NOT belong. 

 2. To allow for the absorption of minerals as non-chelated minerals are reacted with the acid to convert them in to absorbable salts.  

3. Reduction of acid reflux, which results from the lack of stomach acid.  A lack of stomach acid leads to fermentation by yeast overgrowth in the stomach and by fermentation of foods not being digested properly.  The resultant gas formation builds up in the stomach and is eventually rapidly released up the esophagus carrying traces of acid with it.  

4. To allow for the proper digestion of proteins.  The digestive enzyme pepsin cannot work without sufficient levels of hydrochloric acid (stomach acid).  When  proteins are not broken down properly the intact proteins can enter the bloodstream forming antigens.  This in turn can lead to serious and even life threatening allergic reactions.

 5. Absorption of vitamins.  The B vitamins B6, B12 and folate in particular are dependent on sufficient stomach acid for absorption.  Stomach acid levels decline though with age naturally.  This is why deficiencies of B6, B12 and folate are so common in the elderly.  

6. Conversion of silica to orthosilicic acid for use by the body.  Silica is essential for the formation of collagen, elastin, and chondroitin.  Without sufficient silica we develop numerous conditions including osteoporosis, osteoarthritis, heart disease, emphysema, diverticulitis, etc.  Even wrinkles and cellulite can result from a loss of silica leading to a reduction of the structural proteins collagen and elastin.  In order for silica to be absorbed and utilized it must first be converted in to orthosilicic acid.  This occurs from a reaction between silica and water, but the process is greatly enhanced by the presence of an acid.  The primary acid for this conversion is stomach acid. 

As I mentioned before stomach acid DECLINES with age.  This leads to a drop in the conversion of silica in to orthosilicic acid, and therefore a loss of collagen, elastin, and chondroitin production as we age.  Now go back and look at the symptoms that develop from the loss of these structural proteins.  Notice how these are not seen in younger people but are common in the elderly?  So why do we see this in the elderly?  Because the lack of stomach acid interferes with the absorption of nutrients needed for the production of structural proteins.  These nutrients include silica, zinc, copper and amino acids. 

As we can see if you want to speed up the production of “age-related disorders” a simple way is to do this is to neutralize your stomach acid.

It should be noted that most of the nutrients needed to form stomach acid are acid dependant for absorption.  Therefore the lack of stomach acid leads to further declines in stomach acid, leading to less absorption of stomach acid forming nutrients, leading to less stomach acid formation………   It is a vicious cycle downhill once started.  Therefore I recommend avoiding antacids, acid blockers also known as proton pump inhibitors, alkaline waters, calcium carbonate (coral, oyster shell, dolomite), calcium oxide/hydroxide (lime) and magnesium oxide/hydroxide.

Why People Need to be Careful Obtaining Health Advice From the Internet

The internet has made doing medical research so easy, but it has also opened the door to anyone making whatever dubious health claims they wish.

For example, I found a post on Curezone where a woman claimed to have multiple sclerosis (MS) that she assumed was from her amalgam fillings.  According to her story she had the amalgam fillings removed and replaced with gold.  She claims that within 10 days she had no more symptoms of MS.

So what is wrong with the story?  Plenty!

First of all MS is an autoimmune disease caused from a virus and adrenal dysfunction.  It has nothing to do with mercury.

Secondly, even if mercury was involved then the symptoms would not have cleared that quick since mercury is stored in fat tissues including the brain.  It would take a lot longer than 10 days to clear the mercury from the body.  Furthermore, anyone knowing how the body really works would have known that MS causes damage to the myelin that insulates the nerves causing the MS symptoms.  Even if the source of the MS is eliminated the lesions would have to be eliminated somehow and the myelin would have to be regenerated in order for the symptoms to disappear.  The lesions are basically scar tissue and are permanent.  Myelin will regenerate, but this can take many months to years.  For someone to claim that they were symptom free of MS in 10 days just proves beyond a reasonable doubt that the whole story was fabricated!

Despite the literal impossibilities of the story though there were still people buying I to the claims without question.

Another example I have made reference to in the past are the supposed “oleander soup testimonials” that keep getting posted on the internet on various sites.  One problem with these so-called “testimonials” is that there is no way to confirm if any of them are true to begin with.  I have always found it interesting that Dr. Ozel has supposedly cured thousands of patients using “oleander soup” but the same dozen or so “testimonials” are the only “evidence” being presented.  Where are these thousands of patients supposedly cured?  Why aren’t they all over the media praising Dr. Ozel’s name if they are still alive?  Instead, the way these “testimonials” are presented there is no way to confirm if the people really exist.  And if they do are they still alive?  What other therapies did they use in conjunction if any?  Did their cancers come back?

This is a major problem with “testimonials” on the internet.  Anyone can make up fake testimonials and put them up on the internet to mislead people in to thinking these were written by actual people who used the therapy and succeeded.  In fact, if you do a quick search on the internet you will find that there are even companies whose sole business is to write phony testimonials for products.

Therefore, are unverifiable testimonials proof of effectiveness?  Of course not.  But this tactic is used all the time, especially on the internet.  I gave an example in my previous blog post:

https://medreview.wordpress.com/2012/10/19/is-oleander-soup-for-cancer-a-scam-part-2-2/

in which Tony Isaacs claimed the studies showing oleander did not work against cancer failed because they were not conducted long enough.  According to Mr. Isaacs oleander takes at least several months to even start seeing results with oleander.  Yet, Mr. Isaacs keeps posting the same unverifiable “testimonials” that include a supposed complete remission of cancer in 12 days.  Such clear contradictions call all of the unverifiable claims in to question since both completely opposite claims cannot be true.

Don’t get me wrong, testimonials are wonderful.  But only if they are real to begin with and the facts can be verified to confirm a particular treatment is what actually worked.   They are not wonderful when they are too fantastic to be true and clearly contradict real evidence, such as every in vivo oleander study, which has shown it to be ineffective for cancer.

There used to be another poster on Curezone who went by the name Moreless that also touted all sorts of testimonials to his protocol, which included the ingestion of caustic calcium hydroxide.  If anyone questioned him or his dangerous claims they were immediately banned from his forum and were literally told they were Satan or the Satan’s disciples.  He was finally banned from Curezone for pulling stunts such as editing posts on his forum that disagreed with him or discussed the side effects and injuries people had to make the post appear they were agreeing with Moreless and the protocol was safe and effective.

I had a number of people contact me directly through private messages and e-mails discussing their injuries and even hospitalizations after following this protocol.  Of course these testimonials were erased immediately if they were reported on that forum so others would not find out how dangerous his advice really was.

Actually, if anyone looked in to his other claims they would have known better than to follow anything this person claimed.  Some of my favorite ridiculous claims being made by this person included:

  • Sunlight is acidic because it contains a lot of hydrogen.  The fact is that the sunlight does not have a pH.  Light consists of photons, which are elementary particles, not atoms.  Just because a neon light emits light this does not mean that light contains neon atoms.
  • That acidity would turn the tissues in to a “puddle of goo”.  He never did answer my question as to how the parts of the body that were naturally acidic had not dissolved into puddles of goo.  Or why someone running a marathon did not dissolve into a puddle of goo from the acidity generated during intense exercise.
  • That nitrogen is a protein.  Nitrogen is an atom and a diatomic gas, not a protein.
  • That there are subatomic minerals.  If minerals are made up of multiple full size atoms then how can a mineral be smaller than an individual atom?   It’s impossible.

Despite these and other totally ridiculous and dangerous claims made by Moreless he had a cult-like following.  At least in part as it was later revealed that Moreless was using different posting names to make it appear he had more followers than he actually had.  This also brings up the question of how many of the “testimonials” did Moreless fabricate to make his protocol appear effective?

In one post one of his followers claimed she was cured by the Moreless protocol.  But then in another post she wrote “Yes, I have had candida and MCS.  First the candida, then several years later after nothing I did to relieve it worked, very severe MCS.”

And:

“2 1/2 years on the Moreless protocol, getting better every day!!!”

So here was a “success testimonial” from a person who was admitting that after years on the Moreless protocol was still sick.

Isaacs and Moreless are only a couple of the people on Curezone presenting bogus information and giving dangerous advice.

These are just a few examples of some of the bogus, misleading and dangerous health advice I have seen on the internet.  I will be addressing other examples in future blog posts.  The point that was being made is that just because someone makes a health claim on the internet this does not automatically make it true and “testimonials” mean nothing unless the facts can be verified.

It may be nice and easier to just ask someone health advice rather than taking a little personal responsibility and researching the claims from credible sources to see if they are legitimate and safe.

This does not apply only to holistic medicines, but allopathic medicines as well.  I have seen so many people harmed by unnecessary medications and procedures because they did not question their doctors or research their conditions, medications or procedures.

For example, someone I know personally was put on Lasix (furosemide) for over 2 years without potassium, which is a major medical mistake.  Lasix (furosemide) drops potassium levels significantly causing heart arrhythmias.  Instead of giving him potassium though to prevent the side effect of the Lasix he was instead prescribed a very dangerous drug known as Amiodarone, which ended up causing iodine toxicity that has taken months for him to recover from.  All it would have taken to avoid the situation was a little simple research on the drugs to know that the Amiodarone was not necessary and the arrhythmias could have easily been prevented with the safer potassium that was being depleted by the Lasix.

Is “Oleander Soup” Effective for HIV or AIDS?

Is “oleander soup” effective for HIV or AIDS?

The claims of “oleander soup” being effective for cancer have already been debunked.

These are not the only questionable claims that have been made by Tony Isaacs.  Mr. Isaacs has also claimed that oleander has been shown to be effective against HIV/AIDS as well.  As “evidence” he posted a link to an article he wrote for his sales site.  Isaacs article then makes reference to a “100% successful double blind placebo controlled study”, which he claims the complete trial report can be found at:

http://www.tbyil.com/HIV_OPC_Trial.pdf

This is not the actual study, it is a person’s dissertation.  And there are no references to this study, nor can I find the study on Medline.  This calls in to question if the study actually exists and if it does was it conducted and interpreted properly.

Another problem with the claim that this proves oleander is effective is the fact that if this study is for real it was not for oleander alone.  On page 5 of the dissertation it clearly states that they used a mixture of sutherlandia and oleander.  Unlike oleander, there are studies showing strong potential for sutherlandia as an effective treatment for diseases such as cancer.  Here are some journal articles discussing the antiviral activity of sutherlandia:

http://www.nutritionj.com/content/4/1/19

http://journals.lww.com/aidsonline/fulltext/2005/01030/impact_of_african_herbal_medicines_on.13.aspx

To claim that the oleander was effective component is like claiming if someone takes a morphine tablet for pain with water that the water killed the pain.  The only component of the mixture that has shown any significant anti-retroviral activity is the sutherlandia, not the oleander.

The dissertation also states that this study was about raising CD4 counts in a total of 10 HIV+ people.  HIV+ though DOES NOT mean HIV infected.  The HIV antibody test is notoriously inaccurate with over 65 known causes of false positives.

A common cause of low CD4 cell counts in people testing HIV+ is the anti-retroviral drugs they are put on, which the dissertation does mention on page 3. Even though they state that participants could not be currently on anti-retroviral drugs it does not state that they could not have been used previously. And it is known that simply getting off of anti-retroviral drugs can allow the bone marrow to heal, which in turn will allow CD4 counts to come up.  So without knowing if these people were on anti-retroviral drugs before hand it is impossible to say if the herb mixture or simply getting off the anti-retrovirals was really responsible for the increase in CD4 counts.  This is why larger, well designed studies are needed, which have not been done.

On page 29 they mention that the sutherlandia in the formula contains canavanine, which is considered toxic.  It not only raises blood pressure, but it can also aggravate autoimmune conditions like lupus.  And according to this report the long term use can cause symptoms mimicking AIDS (page 2):

http://www.gaiaresearch.co.za/Assets/Images/Pdf/Sutherlandia.pdf

Toxicity of the canavanine in sutherlandia starts of page 4 of the link I posted.

On page 32 of the link supplied by Mr. Isaacs it clearly states that the active components in oleander are polysaccharides as I kept pointing out to Mr. Isaacs.  I also repeatedly pointed out to him that there are many non-toxic sources containing immune stimulating polysaccharides that do not need to be processed to render them non-deadly like oleander.  These include medicinal mushrooms, seaweeds, schisandra, astragalus, echinacea, birch, yeasts, etc.  Many of these sources also contain other anticancer and antiviral compounds.  For example, turkey tail mushrooms contain anticancer and antiviral organic germanium.  Birch bark contains antiviral and anticancer betulinic acid.  Betulinic acid is concentrated in even higher amounts in chaga mushrooms that grow on birch trees.  So why would anyone bother with having to render a toxic plant nontoxic when so many non-toxic sources of polysaccharides exist? Especially when these other things also provide other antitumor compounds.

A cardiac glycoside found in oleander called oleandrin has shown some anti-cancer effects against some cancer cell lines in culture studies, but not in human studies.  Even though Mr, Isaacs has repeatedly claimed this is an active component in “oleander soup” and ignores the fact that oleandrin is lipid soluble and therefore is not extracted in to “oleander soup”, which is a water extract.

One of the statements that I found particularly funny in the dissertation was on page 35 where is states the participants were given soy formula fortified with vitamins and minerals.  Mr. Isaacs has bashed me numerous times for posting the benefits of consuming soy, yet he posts this dissertation where soy was used and that could have accounted for many of the benefits seen in the study.  Soy has been shown in numerous studies to be anti-cancer, and cancer is a common symptom in AIDS.  The vitamins and minerals as well as having some actual food in the form of soy would have also boosted their immune systems of the participants.  Then there is the fact that soy contains antiviral protease inhibitors.  So this puts the entire study in to question since there were several compounds used that could have accounted for any positive effects.

Vitamin C Interactions

Pharmaceutical drugs often react with foods and supplements, including vitamin C.  And as we have seen, excessive vitamin C intake can interact with some nutritional compounds.  Sometimes these interactions are beneficial such as increasing the absorption of minerals.  And sometimes it leads to problems such as iron overload or copper and B12 deficiencies.
Another problem that is often overlooked is the interference of laboratory tests by excessive intake of vitamin C.  For example, excessive vitamin C intake may lead to false high or low bilirubin levels depending on the assay test being used.  Lactate dehydrogenase, cholesterol and triglyceride levels will read erroneously low.  Aspartate aminotransferase levels may read erroneously high.

The National Institute of Health (NIH) reported on a case in which a woman with unexplained anemia was taking 2,000mg of vitamin C daily.  When tested for occult blood in the stool repeated tests showed negative results.  The woman discontinued taking the vitamin C for 4 days, and when retested stool samples tested positive for blood.  It was also found that taking 750mg of vitamin C daily can interfere with detecting blood in stool and urine.

Vitamin C interferes with several glucose tests, including tests diabetics use at home.  Urinary glucose test strips will test false positive with as little as 2,000mg of vitamin C daily.  Home test strips can show normal blood glucose readings even when glucose levels are elevated or with as little as 2g of vitamin C daily.  Laboratory glucose tests may show erroneously low glucose levels with excessive vitamin C intake.

To decrease the risk of false laboratory readings it is recommended that all supplements be stopped at least 48 hours before having any lab work done.

Below is a link from the NIH and a portion of the article that discusses the interactions of vitamin C with drugs and supplements, and interference with laboratory tests.

http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-vitaminc.html

Interactions with Drugs

Acetaminophen (Tylenol): Vitamin C may increase adverse effects associated with acetaminophen.

Antacids: Vitamin C may increase adverse effects associated with aluminum-containing antacids such as aluminum hydroxide (Maalox, Gaviscon).

Aspirin: Vitamin C may increase blood levels and adverse effects of aspirin, whereas aspirin may decrease blood levels of vitamin C.

Barbiturates: The effects of vitamin C may be decreased by barbiturates including phenobarbital (Luminal, Donnatal), pentobarbital (Nembutal), or secobarbital (Seconal).

Fluphenazine (Permitil, Prolixin): Vitamin C supplementation may decrease levels of the drug fluphenazine in the body.

HIV medications (protease inhibitors): Concomitant administration of high doses of vitamin C can reduce steady-state indinavir plasma concentrations.

Levodopa (Dopar, Larodopa): There is limited case report evidence that high dose vitamin C may reduce side effects of levodopa therapy such as nausea or malcoordination.

Nicotine: Nicotine products such as cigarettes, cigars, chewing tobacco, or nicotine patches may decrease the effects of vitamin C.

Oral contraceptives/estrogens: Oral estrogens may decrease the effects of vitamin C in the body. When taken together, vitamin C may increase blood levels of ethinyl estradiol.

Tetracyclines: The effects of vitamin C may be decreased by tetracycline antibiotics such as doxycycline (Vibramycin), minocycline (Minocin), or tetracycline (Sumycin).

Warfarin (Coumadin): Vitamin C in high doses appears to interfere with the blood thinning effects of Warfarin by lowering prothrombin time (PT) as noted in case reports in the 1970s.  Complications have not been reported (such as increased blood clots).

Interactions with Herbs and Dietary Supplements

Iron: When taken together, vitamin C may increase the absorption of iron in the gastrointestinal tract, although this effect appears to be variable and may not be clinically significant.

Lutein: Vitamin C may increase absorption of lutein vitamin supplements.

Vitamin B12 (cobalamin, cyanocobalamin): Large doses of vitamin C may interfere with the absorption and metabolism of vitamin B12.

Interactions with Laboratory Tests

Bilirubin: Vitamin C supplements may cause false increases in tests of blood bilirubin levels.

Carbamazepine levels: Vitamin C supplements may cause false increases in blood carbamazepine levels.

Creatinine: Vitamin C supplements may cause false increases in blood creatinine levels.

Glucose: Vitamin C supplements may interfere with the accuracy of blood glucose tests.

LDH (lactose dehydrogenase): Vitamin C may cause a false decrease in blood LDH levels.

Prothrombin time (PT): Vitamin C in high doses appears to interfere with the blood thinning effects of warfarin by lowering prothrombin time (PT), as noted in case reports in the 1970s. Complications have not been reported (such as increased blood clots).

SGOT (glutamic oxaloacetic transaminase): Vitamin C supplements may cause false increases in blood SGOT levels.

Stool occult blood (guaiac): Vitamin C supplements can cause false-negative stool occult blood tests, within 48-72 hours after vitamin C ingestion.

Theophylline levels: Vitamin C supplements may cause false decreases in blood theophylline levels.

Uric acid levels: Vitamin C supplements may cause false increases in blood uric acid levels.

Urinary acetaminophen (Tylenol): Vitamin C supplements can cause false-negative urine acetaminophen tests.

Urinary glucose: Vitamin C supplements can cause false-positive urinary glucose results with the cupric sulfate reagent test and false-negative urinary glucose results with the glucose oxidase test, within 48-72 hours after vitamin C ingestion.

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